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Review Article
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J Mult Scler. 2012;3(2):33-37. Published online September 1, 2012.
- 시신경척수염: 최신지견
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신하영, 신하영
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연세대학교 의과대학 신경과학교실
연세대학교 의과대학 신경과학교실 -
- Neuromyelitis Optica: What’s New in 2011-2012?
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Ha Young Shin, Ha Young Shin
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Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
Department of Neurology, Yonsei University College of Medicine, Seoul, Korea -
- Abstract
- "Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system, which affects optic nerve and spinal cord preferentially. After the discovery of NMO-IgG in patientsof NMO and the identification of aquaporin 4 as a target of NMO-IgG, the knowledge aboutNMO is growing explosively. Advances in our understanding of the patho-mechanism of NMO haveidentified new targets for future therapeutic efforts, including anti-aquaporin-4 monoclonal antibodyblocker and neutrophil protease inhibition. This review highlights the recent advances in currenttreatment and future therapeutic approaches. Journal of Multiple Sclerosis 3(2):33-37, 2012"
Keywords :Neuromyelitis optica, Devic’s disease, Anti-Aquaporin-4 antibody