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Case Report
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J Mult Scler Neuroimmunol. 2021;12(2):60-63. Published online December 1, 2021.
- 전신홍반루푸스 환자에서 경구 면역억제제 증량 후 발생한 진행성다초점백질뇌병증
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강일모, 이상곤
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한양대학교 의과대학 신경과학교실
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- A Case of Progressive Multifocal Leukoencephalopathy in Systemic Lupus Erythematosus While Titrating Mycophenolate Mofetil with Low-Dose Corticosteroid
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Ilmo Kang, Sanggon Lee
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Department of Neurology, College of Medicine, Hanyang University, Seoul, Korea
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- Abstract
- "Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease caused by the reactivation of human polyomavirus JC in immunosuppressed patients. We report a systemiclupus erythematosus (SLE) patient diagnosed with definite PML after titration of mycophenolatemofetil based on characteristic MRI findings. After all, the patient eventually went through a fatalclinical course. PML should be considered in the differential diagnosis if SLE patient presentswith new-onset focal neurological deficits, even during low-dose immunosuppressive therapy.Journal of Multiple Sclerosis and Neuroimmunology 12(2):60-63, 2021"
Keywords :Leukoencephalopathy, Progressive multifocal; Lupus erythematosus, Systemic; Mycophenolic acid
