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Acute Disseminated Encephalomyelitis in an Elderly Patient

J Mult Scler Neuroimmunol > Volume 12(1); 2021 > Article
Journal of Multiple Sclerosis and Neuroimmunology 2021;12(1):10-14.
Published online January 1, 2021.
노인 환자에서의 급성파종뇌척수염
김상연a, 신현준b, 김고운a,c
a전북대학교 의과대학 전북대학교병원 신경과
b예수병원 신경과
c전북대학교 임상의학연구소 전북대학교병원 의생명연구원
Acute Disseminated Encephalomyelitis in an Elderly Patient
Sang Yeon Kima, Hyun-June Shinb, Ko Woon Kima,c
aDepartment of Neurology, Jeonbuk National University Hospital, School of Medicine, Jeonbuk National University, Jeonju, Korea;
bDepartment of Neurology, Presbyterian Medical Center, Jeonju, Korea;
cResearch Institute of Clinical Medicine of Jeonbuk National University-Biomedical Research Institute of Jeonbuk National University Hospital, Jeonju, Korea
Abstract
"Acute disseminated encephalomyelitis (ADEM) is a demyelinating central nervous system disease involving various brain lesions requiring differential diagnosis. A 63-year-old man presented with psychiatric symptoms and abulia. The patient’s symptoms improved after treatment with high-dose steroids but recurred as a tumefactive lesion related to early steroid tapering due to complication. The patient was diagnosed with ADEM through brain biopsy after excluding other demyelinating diseases and autoimmune encephalitis based on various laboratory tests. The patient completely recovered after administration of a sufficient duration of steroid treatment. This report suggests that long-term steroid treatment or alternative immunosuppressive agents should be considered in ADEM patients with diabetes. Journal of Multiple Sclerosis and Neuroimmunology 12(1):10-14, 2021"
Key Words: Key Words: Encephalomyelitis, Acute disseminated, Magnetic resonance imaging, Biopsy
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