J Mult Scler > Volume 2(1); 2011 > Article
Journal of Multiple Sclerosis 2011;2(1):16-19.
Published online March 1, 2011.
NMO-IgG 양성 환자에서 숨뇌 병변에 의하여 발생된 난치성 구토 1예
신하영, 이정환, 이기정, 선우일남, 김승민
연세대학교 의과대학 신경과학교실
Intractable Vomiting Caused by Medulla Oblongata Lesions in a NMO-IgG Positive Patient
Ha Young Shin, Jung Whan Lee, Ki Jeong Lee, Il Nam Sunwoo, Seung Min Kim
Department of Neurology, Yonsei University College of Medicine, Seoul, Korea
Abstract
"NMO-IgG is highly specific for neuromyelitis optica and reacts with the water channel aquaporin 4, which expressed particularly in the periventricular and periaqueductal areas, including dorsomedial regions of the medulla oblongata, where emetic circuitry may exist. We report an intractable vomiting in a NMO-IgG positive patient. She suffered from recurrent myelitis. Brain MRI revealed a single focal T2 high signal intensity in the area postrema or nucleus tractus solitaries. Intractable vomiting may be caused by neuromyelitis optica spectrum disorder. Journal of Multiple Sclerosis 2(1):16-19, 2011"
Key Words: Neuromyelitis optica, Intractable vomiting, Nucleus tractus solitaries
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