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Successful Treatment of Chronic Inflammatory Demyelinating Polyradiculoneuropathy with Rituximab

J Mult Scler Neuroimmunol > Volume 12(2); 2021 > Article
Journal of Multiple Sclerosis and Neuroimmunology 2021;12(2):39-42.
Published online December 1, 2021.
리툭시맙에 치료효과를 보인 만성염증탈수초다발신경병
김다영, 최교민, 오지영
건국대학교병원 신경과
Successful Treatment of Chronic Inflammatory Demyelinating Polyradiculoneuropathy with Rituximab
Dayoung Kim, Kyomin Choi, Jeeyoung Oh
Department of Neurology, Konkuk University Medical Center, Seoul, Korea
Abstract
"Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a heterogeneous autoimmune disease characterized by a relapsing and remitting or progressive pattern. Corticosteroid, intravenous immunoglobulin or plasma exchange are usually used as treatment options. However, approximately one-third of patients with CIDP have an inadequate response to standard treatments. Rituximab, a monoclonal antibody against CD20, has been used with good results in some patients with refractory CIDP. We report a patient with refractory CIDP in whom remission has been successfully maintained after treatment with rituximab. Journal of Multiple Sclerosis and Neuroimmunology 12(2):39-42, 2021"
Key Words: Polyradiculoneuropathy, Chronic inflammatory demyelinatin, Rituximab


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