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A Case of Stiff-person Syndrome with Hodgkin Disease

J Mult Scler > Volume 9(1); 2018 > Article
Journal of Multiple Sclerosis 2018;9(1):10-13.
Published online March 1, 2018.
호지킨병이 발병한 강직증후군 환자의 증례
김주현1,2, 박재홍1, 최은혁1, 민주홍1,2, 김병준1,2
1성균관대학교 의과대학 삼성서울병원 신경과
2삼성서울병원 뇌신경센터
A Case of Stiff-person Syndrome with Hodgkin Disease
Juhyeon Kim1,2, Jea-Hong Park1, Eun-Hyeok Choi1, Ju-Hong Min1,2, Byoung-Joon Kim1,2
1Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
2Neuroscience Center, Samsung Medical Center, Seoul, Korea
Abstract
"Stiff-person syndrome (SPS) is characterised by progressive rigidity and muscle spasms affecting the axial and limb muscles. Autoantibodies to the GABA-synthesizing enzyme glutamic acid decarboxylase,present in about 60-85% of patients, have indicated an autoimmune pathogenesis.Thus, other autoimmune diseases may occur or, rarely, neoplasms may occur together. We report acase of a patient diagnosed with SPS at the age of 20 who was diagnosed with Hodgkin disease 4years later.Journal of Multiple Sclerosis 9(1):10-13, 2018"
Key Words: Stiff-person syndrome, Autoimmune disease, Hodgkin disease
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