Multiple Sclerosis Presenting as Paroxysmal Paresthesia

Lee, Wonwoo; Baik, Minyoul; Shin, Ha Young

J Mult Scler > Volume 7(1); 2016 > Article

Case Report

Journal of Multiple Sclerosis 2016;7(1):21-24.
Published online March 1, 2016.

돌발적인 저린 증상으로 발현한 다발경화증

이원우, 백민렬, 신하영

연세대학교 의과대학 세브란스병원 신경과

Multiple Sclerosis Presenting as Paroxysmal Paresthesia

Wonwoo Lee, Minyoul Baik, Ha Young Shin

Multiple Sclerosis Presenting as Paroxysmal Paresthesia

Abstract

"Many patients with multiple sclerosis suffer from paroxysmal symptoms such as tonic spasm or paroxysmal ataxia but they are frequently overlooked by patients and also doctors, delaying diagnosisand treatment. Paroxysmal paresthesia or numbness is an even more rare manifestation. A femalepatient presented paroxysmal paresthesia which resolved spontaneously. The symptoms were dueto multiple sclerosis and the symptoms did not recur after treatment with interferon beta. Pulse generation,re-excitation in demyelinated fiber and ephaptic transmission are suggested as pathophysiology. Journal of Multiple Sclerosis 7(1):21-24, 2016"

Key Words: Multiple sclerosis, Paroxysmal symptoms, Paroxysmal paresthesia