Significant Improvement of Spasticity with Intrathecal Baclofen Pump Implantation in a Patient with Multiple Sclerosis

Hyun, Jae-Won; Kim, Su-Hyun; Jeong, In Hye; Kim, Jae-Hyun; Kim, Dae Hyun; Kim, Ho Jin

J Mult Scler > Volume 6(2); 2015 > Article

Case Report

Journal of Multiple Sclerosis 2015;6(2):40-43.
Published online September 1, 2015.

척수강 내 Baclofen 주입 펌프 이식술로 현저한 양하지 강직의 호전을 보인 다발성경화증 환자 1예

현재원¹, 김수현¹, 정인혜¹, 김재현², 김대현², 김호진¹

^¹국립암센터 신경과
^²국립암센터 마취통증의학과

Significant Improvement of Spasticity with Intrathecal Baclofen Pump Implantation in a Patient with Multiple Sclerosis

Jae-Won Hyun¹, Su-Hyun Kim¹, In Hye Jeong¹, Jae-Hyun Kim², Dae Hyun Kim², Ho Jin Kim¹

¹Department of Neurology, Research Institute and Hospital of National Cancer Center, Goyang, Korea
²Anesthesiology and Pain Medicine, Research Institute and Hospital of National Cancer Center, Goyang, Korea

Abstract

"Spasticity is one of the symptoms of multiple sclerosis (MS) that increasingly impairs function and quality of life as the disease progresses. It is a complex problem that can lead to disability and secondarycomplications such as pressure sores and contractures. Therapeutic options include oral medications,but these have limited effectiveness and often cause side effects that limit dose titration. Incarefully selected patients, intrathecal baclofen can reduce spasticity and improve patient functionand comfort with fewer side effects than oral medications. Herein, we describe a patient with MSwhose symptoms of spasticity improved remarkably following intrathecal baclofen pump implantation.This article illustrates that intrathecal baclofen pump implantation is a useful symptomatic treatmentchoice in MS patients with severe spasticity. Journal of Multiple Sclerosis 6(2):40-43, 2015"

Key Words: Multiple sclerosis, Spasticity, Intrathecal, Baclofen