Advanced MRI techniques in Multiple Sclerosis

Kim, Nam-Hee

J Mult Scler > Volume 4(2); 2013 > Article

Review Article

Journal of Multiple Sclerosis 2013;4(2):36-43.
Published online September 1, 2013.

다발성경화증의 새로운 MRI 기법들

김남희

동국대학교 의과대학 일산병원 신경과학교실

Advanced MRI techniques in Multiple Sclerosis

Nam-Hee Kim

Department of Neurology, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea

Abstract

"Magnetic resonance imaging (MRI) has rapidly become a leading research tool in the investigation of multiple sclerosis (MS). Recent technical advances made progress in understanding the substrateand mechanisms underlying the development and evolution of focal lesions and ‘diffuse’ damagein MS as well as the functional consequences of such structural abnormalities. Higher-field MRscanners and new positron emission tomography (PET) radio ligands has provided new insights intocellular and pathophysiological abnormalities, and would be valuable in future therapeutic trials. Thisreview summarizes advanced MRI approaches for the investigation of lesion burden and understandingof the pathophysiology of MS. Journal of Multiple Sclerosis 4(2):36-43, 2013"

Key Words: Multiple sclerosis, Magnetic resonance imaging, Ultra-high field, Double inversion recovery, Iron