Two Cases of Herpes Zoster Myelitis Elicited by Immune-mediated Mechanism

Kim, Ji-Sun; Jang, Jae-Hong; Kim, Byung-Jo

J Mult Scler > Volume 4(2); 2013 > Article

Case Report

Journal of Multiple Sclerosis 2013;4(2):61-64.
Published online September 1, 2013.

면역매개반응으로 인해 발생한 대상포진척수염 2예

김지선, 장재홍, 김병조

고려대학교 의과대학 신경과학교실

Two Cases of Herpes Zoster Myelitis Elicited by Immune-mediated Mechanism

Ji-Sun Kim, Jae-Hong Jang, Byung-Jo Kim

Department of Neurology, Korea University College of Medicine, Seoul, Korea

Abstract

"Herpes zoster myelitis (HZM) is one of serious complications of herpes zoster infection. Although HZM is recognized as a complication mainly occur in immunocompromised patients, HZM in immunocompetentpatients have been reported increasingly. We reported two cases of HZM in immunocompetentpatients. Based on favorable prognosis and no previous evidence of viral invasionin spinal cord, we suggest that the pathomechanism of HZM in immunocompetent patients is immune-mediated pathogenesis rather than direct invasion of zoster virus. Journal of Multiple Sclerosis 4(2):61-64, 2013"

Key Words: Herpes zoster, Myelitis, Immune system diseases