A Case of Progressive Myelitis Caused by Varicella Zoster Virus Infection

Lee, In Kyung; Lee, In Kyung; Lee, Seung-Hwan; Lee, Seung-Hwan; Kim, Sung Hun; Kim, Sung Hun

J Mult Scler > Volume 3(2); 2012 > Article

Case Report

Journal of Multiple Sclerosis 2012;3(2):55-58.
Published online September 1, 2012.

대상포진에 의한 진행성 척수염 증례 1예

이인경, 이인경, 이승환, 이승환, 김성훈, 김성훈

강원대학교 의학전문대학원 신경과학교실
강원대학교 의학전문대학원 신경과학교실

A Case of Progressive Myelitis Caused by Varicella Zoster Virus Infection

In Kyung Lee, In Kyung Lee, Seung-Hwan Lee, Seung-Hwan Lee, Sung Hun Kim, Sung Hun Kim

Department of Neurology, Kangwon National University School of Medicine, Chuncheon, Korea
Department of Neurology, Kangwon National University School of Medicine, Chuncheon, Korea

Abstract

"Myelitis caused by varicella zoster virus (VZV) infection is a very rare neurological complication although its mechanism has been poorly understood. We present a 75-year-old man who presentedvesicular skin eruption of herpes zoster followed by recurrent myelitis in spite of continuous treatmentwith anti-viral medication. Serial analysis of cerebrospinal fluid demonstrated sustained highlevel IgG antibody for VZV. We suspected that immune-mediated mechanism could be the cause ofprogressive myelitis in our patient. Journal of Multiple Sclerosis 3(2):55-58, 2012"

Key Words: Myelitis, Varicella zoster virus, Antibody, Immune-mediated mechanism