Update of Multiple Sclerosis

Kim, Sun-Young; Kim, Sun-Young

J Mult Scler > Volume 3(1); 2012 > Article

Review Article

Journal of Multiple Sclerosis 2012;3(1):13-19.
Published online March 1, 2012.

다발성 경화증의 최신지견

김선영, 김선영

울산대학교 의과대학 신경과학교실, 울산대학교병원 신경과
울산대학교 의과대학 신경과학교실,
울산대학교병원 신경과

Update of Multiple Sclerosis

Sun-Young Kim, Sun-Young Kim

Department of Neurology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea
Department of Neurology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea

Abstract

"In the last decade of the 20th century, the development of pharmacological agents for MS paralleled advances in the understanding of disease pathophysiology, in neuroimmunology, and in neuroimaging.Although MS was previously thought to be primarily a disease of CNS myelin, recent neuropathologicstudies have confirmed the evidence of axonal injury in both the early and late stages of the illness.The knowledge about early intervention leads us to revise the diagnostic criteria for MS, whichshould be required to prevent further axonal damage. Consequently, this article will provide ageneral overview of MS, focusing on current concepts of diagnostic criteria, pathology/pathogenesis,and risk factors. Journal of Multiple Sclerosis 3(1):13-19, 2012"

Key Words: Multiple sclerosis, MGNIMS criteria, Cortical pathology, Chronic venous insufficiency