| Neuromyelitis Optica Spectrum Disorders: Diagnostic Issues in Korea |
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Ju-Hong Min |
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Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea |
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| Abstract |
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"Neuromyelitis optica (NMO) is a CNS demyelinating disorder, characterized by optic neuritis and acute myelitis. A specific autoantibody of NMO, NMO-IgG was recently detected, which resulted in the revision of the diagnostic criteria of NMO, proposed in 1999. The new diagnostic criteria emphasized the long cord lesion over 3 vertebral segments and the presence of NMO-IgG. In addition, with the positivity of NMO-IgG in longitudinal extensive myelitis, recurrent optic neuritis and autoimmune disorders, the spectrum of NMO-related disorders were broadened. The review for NMO spectrum disorders and NMO-IgG will provide a help to understand NMO, this rapidly disabling disease. Journal of Multiple Sclerosis 2(1):5-10, 2011" |
| Key Words:
Neuromyelitis optica, Myelitis, Optic neuritis |
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