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A Case of Neuromyelitis Optica Combined With Sjogren’s Syndrome Presenting Posterior Reversible Encephalopathy Syndrome

J Mult Scler > Volume 1(1); 2010 > Article
Journal of Multiple Sclerosis 2010;1(1):27-29.
Published online March 1, 2010.
A Case of Neuromyelitis Optica Combined With Sjogren’s Syndrome Presenting Posterior Reversible Encephalopathy Syndrome
Jaechun Hwang, Byoung Joon Kim, Kwang Ho Lee
Department of Neurology, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea
Abstract
"Posterior reversible encephalopathy syndrome (PRES) is characterized by vasogenic subcortical edema, and its pathogenesis remains not well understood. Here we describe a patient of neuromyelitis optica (NMO) combined with Sjogren’s syndrome (SS) presenting PRES. The patient had relapsing-remitting optic neuritis and myelitis and acutely developed confusion and hemiparesis. Brain MRI revealed massive subcortical lesions. Autoantibodies and diagnostic tests satisfied the diagnostic criteria of SS. Anit-aquaporin-4 antibody was positive. Common water flux impairment may predispose NMO and SS to PRES. Journal of Multiple Sclerosis 1(1):27-29, 2010"
Key Words: PRES, Sjogren’s syndrome, Neuromyelitis optica


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