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Recurrent Hypertrophic Pachymeningitis Successfully Treated with Cyclophosphamide

J Mult Scler Neuroimmunol > Volume 12(2); 2021 > Article
Journal of Multiple Sclerosis and Neuroimmunology 2021;12(2):43-46.
Published online December 1, 2021.
Cyclophosphamide로 치료된 재발 특발비후경수막염
엄현종, 김민경, 신지혜, 김지현
고려대학교 의과대학 구로병원 신경과
Recurrent Hypertrophic Pachymeningitis Successfully Treated with Cyclophosphamide
Hyunjong Eom, Min Kyung Kim, Ji Hye Shin, Ji Hyun Kim
Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea
Abstract
"Hypertrophic pachymeningitis is a inflammatory disorder that causes fibrous thickening of the dura mater, presenting with headache, diplopia, focal deficit, and seizure. High-dose corticosteroid is generally accepted as the first-line treatment. Some cases were reported to be refractory to corticosteroid, and immunosuppressive drugs lead to clinicoradiologic resolution in such cases. Herein, we reported a patient with relapsing idiopathic hypertrophic pachymeningitis in whom neurological symptoms and radiological abnormalities were refractory to corticosteroids and were successfully reversed with cyclophosphamide treatment. Journal of Multiple Sclerosis and Neuroimmunology 12(2):43-46, 2021"
Key Words: Idiopathic hypertrophic pachymeningitis, Methylprednisolone, Cyclophosphamide


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