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Delayed Hepatitis B Reactivation after Repeated Rituximab Treatments for Neuromyelitis Optica Spectrum Disorder

J Mult Scler Neuroimmunol > Volume 12(2); 2021 > Article
Journal of Multiple Sclerosis and Neuroimmunology 2021;12(2):35-38.
Published online December 1, 2021.
시신경척수염 환자에서 리툭시맙 반복 투여 후 발생한 지연성 B형 간염의 재활성화
이혜선, 성의현, 성원재, 김승현
한양대학교 의과대학 신경과학교실
Delayed Hepatitis B Reactivation after Repeated Rituximab Treatments for Neuromyelitis Optica Spectrum Disorder
Hyesun Lee, Euihyun Sung, Wonjae Sung, Seung Hyun Kim
Department of Neurology, Hanyang University College of Medicine, Seoul, Korea
Abstract
"Rituximab is a chimeric mouse human anti-CD20 monoclonal antibody that can reduce B cell numbers and antibody levels and has been prescribed for refractory neuromyelitis optica spectrum disorder (NMOSD). We report a case of delayed hepatitis B reactivation after repeated rituximab treatments with antibodies against aquaporin-4 in a seropositive NMOSD patient with chronic hepatitis B infection. Journal of Multiple Sclerosis and Neuroimmunology 12(2):35-38, 2021"
Key Words: Neuromyelitis optica, Hepatitis B, Rituximab


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