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Case Reports of Clinical Variability in Myelin Oligodendrocyte Glycoprotein (MOG ) Encephalom yelitis Patients

J Mult Scler > Volume 10(2); 2019 > Article
Journal of Multiple Sclerosis 2019;10(2):32-35.
Published online September 1, 2019.
마이엘린 희소돌기아교세포 당단백질(Myelin Oligodendrocyte Glycoprotein) 자가항체 양성뇌척수염 환자들의 임상적 다양성에 대한 증례보고 2예
김성현, 곽동원, 오지영, 최교민
건국대학교병원 신경과
Case Reports of Clinical Variability in Myelin Oligodendrocyte Glycoprotein (MOG ) Encephalom yelitis Patients
Sung Hyun Kim, Dong Won Kwack, Jeeyoung Oh, Kyomin Choi
Department of Neurology, Konkuk University Medical Center, Seoul, Korea
Abstract
"Most experts now consider myelin oligodendrocyte glycoprotein (MOG) antibody positive encepha- lomyelitis as a disease entity immunopathogenetically distinct from multiple sclerosis and neuro-myelitis optica spectrum disorder (NMOSD). MOG-encephalomyelitis patients usually present withrecurrent optic neuritis or limb paralysis due to myelitis, but also behavioral change, seizures, or en- cephalopathies are often the first manifestations in these patients. Herein, we report two cases ofMOG-antibody encephalomyelitis who presented with atypical symptoms that included aggressivebehavior, multiple cranial neuropathies, and seizures.Journal of Multiple Sclerosis 10(2):32-35, 2019
Key Words: Myelin-oligodendrocyte glycoprotein, Encephalomyelitis, Magnetic resonance imaging


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