What’s New in 2014-2015: Neuromyelitis Optica

Lee, Seon Ah; Kim, Jee-Eun

J Mult Scler > Volume 7(1); 2016 > Article

Review Article

Journal of Multiple Sclerosis 2016;7(1):1-8.
Published online March 1, 2016.

시신경척수염의 최신지견: 2014-2015년

이선아¹, 김지은²

^¹서울의료원 의학연구소
^²서울의료원 신경과

What’s New in 2014-2015: Neuromyelitis Optica

Seon Ah Lee¹, Jee-Eun Kim²

¹Research Institute, Seoul Medical Center
²Department of Neurology, Seoul Medical Center, Seoul, Korea

Abstract

"Neuromyelitis optica (NMO) is another idiopathic, severe demyelinating disease that preferentially involves optic nerves and spinal cord. NMO has been frequently misclassified as multiple sclerosis(MS) previously due to its similar clinical presentation. However, growing knowledge of NMO enablesclinician to differentiate it from MS by clinical, laboratory (especially by presence of aquaporin-4 antibodies), neuroimaging, and pathological characteristics. In 2014-2015, there were strikingefforts to integrate the knowledge of NMO and to suggest more sensitive and accurate diagnosticcriteria by international panel. In this review, we summarized recently obtained knowledge of NMOfocusing its clinical and laboratory findings, therapy and highlighted the new diagnostic criteria forNMO, 2015. Journal of Multiple Sclerosis 7(1):1-8, 2016"

Key Words: Neuromyelitis optica, Diagnostic criteria, Biomarkers, Therapy