| 임상적단독증후군의 임상진료지침: 1부. 평가와 진단 |
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김수현1, 박민수2, 강사윤3, 김남희4, 김선영5, 김성민6, 김지영7, 남태승8, 민주홍9, 신하영10, 오지영11, 조정희12, 조중양13, 허소영14, 김우준15, 권오현16 |
1국립암센터 신경과학교실
2영남대학교 의과대학 영남대학교병원 신경과학교실
3제주대학교 의과대학 제주대학교병원 신경과학교실 |
| Clinical Practice Guideline of Clinically Isolated Syndrome: Part I. Evaluation and Diagnosis |
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Su-Hyun Kim1, Min Su Park2, Sa Yoon Kang3, Nam-Hee Kim4, Sun-Young Kim5, Sung-Min Kim6, Jee Young Kim7, Tai-seung Nam8, Ju-Hong Min9, Ha Young Shin10, Jeeyoung Oh11, Jung Hee Cho12, Joong-Yang Cho13, So-Young Huh14, Woojun Kim15, Ohyun Kwon16 |
1Department of Neurology, Research Institute and Hospital of National Cancer Center
2Department of Neurology, Yeungnam Medical
Center, Yeungnam University College of Medicine
3Department of Neurology, Jeju National University Hospital, Jeju University
College of Medicine |
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| Abstract |
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"Clinically isolated syndrome (CIS) is the typical first clinical episode that is highly suggestive of multiple sclerosis (MS). Without diagnostic marker, diagnosing CIS is exactly alike diagnosing MS witheven less evidences and requires careful and integrative interpretation of clinical, radiological andimmunological findings. In the aspect of management, numerous clinical trials and cohort studiesstrongly support prompt start of disease modifying therapies even in the stage of CIS to prevent disabilityaccumulation with disease activity. This guideline covers sequential stages of clinical practice- encounter, assessment, diagnosis, and management - and addresses their principal evidences tohelp clinicians make correct diagnosis and proper management. Though it cannot be emphasizedtoo much to consider every possible differential diagnosis other than MS thoroughly when we encounterpatients with CIS, the details regarding differential diagnosis are out of the scope of thisguideline. The guideline would be regularly updated and revised every a few years to serve its role. Journal of Multiple Sclerosis 7(2):29-39, 2016" |
| Key Words:
Key Words: Clinically isolated syndrome, Evaluation, Diagnosis, Guideline |
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