Recurrent Fever and Menigismus as a Manifestation of Myelin Oligodendrocyte Glycoprotein Antibody Disease

Song, Tae-Jin; Kim, Jee-Eun

J Mult Scler Neuroimmunol > Volume 12(1); 2021 > Article

Case Report

Journal of Multiple Sclerosis and Neuroimmunology 2021;12(1):6-9.
Published online January 1, 2021.

고열을 동반한 수막증으로 반복 발현한 Myelin Oligodendrocyte Glycoprotein 항체 질환

송태진, 김지은

이화여자대학교 의과대학 신경과학교실

Recurrent Fever and Menigismus as a Manifestation of Myelin Oligodendrocyte Glycoprotein Antibody Disease

Tae-Jin Song, Jee-Eun Kim

Department of Neurology, College of Medicine, Ewha Womans University, Seoul, Korea

Abstract

"Isolated meningismus is a rare presentation in both seropositive and seronegative neuromyelitis optica spectrum disorder (NMOSD). Here, we present a case with recurrent fever and meningismus with anti-myelin oligodendrocyte glycoprotein (MOG) antibodies who did not precede to other demyelinating manifestations and showed excellent response to highdose steroid treatment. This case reinforces that isolated meningismus mimicking recurrent meningitis can occur as a direct clinical phenotype of MOG antibody disease rather than antecedent infection triggering further demyelinating attack.Journal of Multiple Sclerosis and Neuroimmunology 12(1):6-9, 2021"

Key Words: Key Words: Anti-MOG antibodies, Neuromyelitis optica spectrum disorder, Myelin oligodendrocyte glycoprotein antibody disease, Meningism