Seronegative Neuromyelitis Optica Spectrum Disorder and Tuberculosis: A Case Report and Literature Review

Min, Young Gi; Hong, Yoon-Ho

J Mult Scler Neuroimmunol > Volume 11(1); 2020 > Article

Case Report

Journal of Multiple Sclerosis and Neuroimmunology 2020;11(1):21-24.
Published online March 1, 2020.

혈청 음성 시신경척수염범주질환과 결핵: 증례보고 및 문헌고찰

민영기^a,b, 홍윤호^b

^a서울대학교병원 신경과
^b서울특별시보라매병원 신경과

Seronegative Neuromyelitis Optica Spectrum Disorder and Tuberculosis: A Case Report and Literature Review

Young Gi Min^a,b, Yoon-Ho Hong^b

^aDepartment of Neurology, Seoul National University Hospital, Seoul, Korea
^bDepartment of Neurology, Seoul National University-Seoul Metropolitan Government Boramae Medical Center, Seoul, Korea

Abstract

"Neuromyelitis optica spectrum disorder (NMOSD) is an autoimmune demyelinating disease of the central nervous system that preferentially involves the optic nerve and spinal cord. We report a patient who presented with acute transverse myelitis in the cervical spinal cord that extended to the lower brainstem in whom active pulmonary tuberculosis (TB) was diagnosed simultaneously. This report adds to the literature on the possible association between active TB and seronegative NMOSD and highlights the need for special considerations in treating these two conditions concurrently.
Journal of Multiple Sclerosis and Neuroimmunology 11(1):21-24, 2020"

Key Words: Neuromyelitis optica spectrum disorders, Tuberculosis, Immunotherapy