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Effectiveness of First-line Natalizumab Treatment in Patients with Highly Active Relapsing-remitting Multiple Sclerosis

J Mult Scler > Volume 9(2); 2018 > Article
Journal of Multiple Sclerosis 2018;9(2):21-23.
Published online September 1, 2018.
질환 활성도가 높은 다발성경화증 환자에서 나탈리주맙 일차 치료의 효과
김수현, 김호진
국립암센터 신경과
Effectiveness of First-line Natalizumab Treatment in Patients with Highly Active Relapsing-remitting Multiple Sclerosis
Su-Hyun Kim, Ho Jin Kim
Department of Neurology, Research Institute and Hospital of National Cancer Center, Goyang, Korea
Abstract
"Patients with highly active relapsing-remitting multiple sclerosis (RRMS) may benefit from early aggressive therapy instead of the escalation approach. Here we describe the outcome of a patient withhighly active RRMS (two relapses in the year after onset and a few gadolinium-enhancing lesions onbrain MRI) treated with natalizumab as a first-line treatment. Over 2 years of natalizumab treatment,no evidence of disease activity was observed. An early aggressive approach may improve treatmentoutcome in patients with highly active RRMS. Journal of Multiple Sclerosis 9(2):21-23, 2018"
Key Words: Multiple sclerosis, Natalizumab


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