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The Strategy of Treatment of Neuromyelitis Optica Spectrum Disorder

J Mult Scler > Volume 6(1); 2015 > Article
Journal of Multiple Sclerosis 2015;6(1):1-8.
Published online March 1, 2015.
시신경척수염의 치료전략
허소영1, 허소영1, 김수현2, 김수현2, 김호진2, 김호진2
1고신대학교 의과대학 신경과학교실
2국립암센터 신경과
1,고신대학교 의과대학 신경과학교실
2 국립암센터 신경과
The Strategy of Treatment of Neuromyelitis Optica Spectrum Disorder
So-young Huh1, So-young Huh1, Su-Hyun Kim2, Su-Hyun Kim2, Ho Jin Kim2, Ho Jin Kim2
1Department of Neurology, Kosin University College of Medicine, Busan, Korea
2Department of Neurology, Research Institute and Hospital of National Cancer Center, Goyang, Korea
1,Department of Neurology,
2
Abstract
"Neuromyelitis optica (NMO) is an autoimmune inflammatory disorder of central nerve system that is characterized by severe optic neuritis and transeverse myelitis. Since the discovery of anti-aquaporin4 antibodies, the concept of NMO has expanded as a NMO spectrum disorder (NMOSD),which is distinct from multiple sclerosis. As NMOSD often causes severe disability, early initiation ofeffective therapy is very important to prevent attack-related disability. Although there are no level I orII evidence studies for NMO treatment, cumulated clinical experience for NMO treatment over thelast decade brought growing body of evidence for the use of immunosuppressive agents. We reviewthe various therapeutic options for NMOSD and propose treatment strategies based on previousreports. Journal of Multiple Sclerosis 6(1):1-8, 2015"
Key Words: Neuromyelitis optica, Neuromyelitis optic spectrum disorder, Treatment


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